Lleida Bat Lyssavirus isolation in Miniopterus schreibersii in France

Zoonoses Public Health. 2019 Mar;66(2):254-258. doi: 10.1111/zph.12535. Epub 2018 Nov 20.

Abstract

Bat rabies cases are attributed in Europe to five different Lyssavirus species of 16 recognized Lyssavirus species causing rabies. One of the most genetically divergent Lyssavirus spp. has been detected in a dead Miniopterus schreibersii bat in France. Brain samples were found positive for the presence of antigen, infectious virus and viral RNA by classical virological methods and molecular methods respectively. The complete genome sequence was determined by next-generation sequencing. The analysis of the complete genome sequence confirmed the presence of Lleida bat lyssavirus (LLEBV) in bats in France with 99.7% of nucleotide identity with the Spanish LLEBV strain (KY006983).

Keywords: LLEBV; bat; rabies.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain / virology
  • Chiroptera / virology*
  • Genome, Viral
  • High-Throughput Nucleotide Sequencing
  • Lyssavirus / genetics
  • Lyssavirus / isolation & purification*
  • Phylogeny
  • RNA, Viral / analysis*
  • RNA, Viral / genetics
  • Rabies / virology
  • Rhabdoviridae Infections / veterinary*
  • Rhabdoviridae Infections / virology

Substances

  • RNA, Viral

Associated data

  • GENBANK/KY006983.1