Clinical implications of fracture-associated vascular damage in extremity and pelvic trauma

BMC Musculoskelet Disord. 2018 Nov 20;19(1):404. doi: 10.1186/s12891-018-2333-y.

Abstract

Background: Vascular damage in polytrauma patients is associated with high mortality and morbidity. Therefore, specific clinical implications of vascular damage with fractures in major trauma patients are reassessed.

Methods: This comprehensive nine-year retrospective single center cohort study analyzed demography, laboratory, treatment and outcome data from 3689 patients, 64 patients with fracture-associated vascular injuries were identified and were compared to a control group.

Results: Vascular damage occurred in 7% of patients with upper and lower limb and pelvic fractures admitted to the trauma room. Overall survival was 80% in pelvic fracture and 97% in extremity fracture patients and comparable to non-vascular trauma patients. Additional arterial damage required substantial fluid administration and was visible as significantly anemia and disturbed coagulation tests upon admission. Open procedures were done in over 80% of peripheral extremity vascular damage. Endovascular procedures were predominant (87%) in pelvic injury.

Conclusion: Vascular damage is associated with high mortality rates especially in combination with pelvic fractures. Initial anemia, disturbed coagulation tests and the need for extensive pre-clinical fluid substitution were observed in the cohort with vascular damage. Therefore, fast diagnosis and early interventional and surgical procedures are necessary to optimize patient-specific outcome.

Keywords: Endovascular repair; Extremity trauma; Fracture-associated vascular damage; Level of evidence: IV; Pelvic trauma; Surgical trauma room.

MeSH terms

  • Adult
  • Aged
  • Cohort Studies
  • Female
  • Fractures, Bone / complications
  • Fractures, Bone / diagnostic imaging*
  • Fractures, Bone / surgery
  • Hemorrhage / diagnostic imaging*
  • Hemorrhage / etiology
  • Hemorrhage / surgery
  • Humans
  • Lower Extremity / diagnostic imaging
  • Lower Extremity / injuries
  • Lower Extremity / surgery
  • Male
  • Middle Aged
  • Pelvic Bones / blood supply*
  • Pelvic Bones / diagnostic imaging*
  • Pelvic Bones / surgery
  • Retrospective Studies
  • Upper Extremity / diagnostic imaging
  • Upper Extremity / injuries
  • Upper Extremity / surgery
  • Vascular System Injuries / diagnostic imaging*
  • Vascular System Injuries / etiology
  • Vascular System Injuries / surgery