Fruit fly research in China

J Genet Genomics. 2018 Nov 20;45(11):583-592. doi: 10.1016/j.jgg.2018.09.003. Epub 2018 Nov 3.

Abstract

Served as a model organism over a century, fruit fly has significantly pushed forward the development of global scientific research, including in China. The high similarity in genomic features between fruit fly and human enables this tiny insect to benefit the biomedical studies of human diseases. In the past decades, Chinese biologists have used fruit fly to make numerous achievements on understanding the fundamental questions in many diverse areas of biology. Here, we review some of the recent fruit fly studies in China, and mainly focus on those studies in the fields of stem cell biology, cancer therapy and regeneration medicine, neurological disorders and epigenetics.

Keywords: China; Development; Epigenetics; Fruit fly; Genetics; Neurology; Signaling pathway.

Publication types

  • Review

MeSH terms

  • Animals
  • Biomedical Research
  • China
  • Disease Models, Animal
  • Drosophila / genetics*
  • Drosophila / metabolism
  • Humans
  • Neoplasms / genetics
  • Neoplasms / metabolism
  • Neoplasms / therapy
  • Nervous System Diseases / genetics
  • Nervous System Diseases / metabolism
  • Nervous System Diseases / therapy