Oral Cavity Cancer

Kyle S Ettinger; Laurent Ganry; Rui P Fernandes

doi:10.1016/j.coms.2018.08.002

Oral Cavity Cancer

Oral Maxillofac Surg Clin North Am. 2019 Feb;31(1):13-29. doi: 10.1016/j.coms.2018.08.002. Epub 2018 Oct 25.

Authors

Kyle S Ettinger¹, Laurent Ganry², Rui P Fernandes³

Affiliations

¹ Division of Oral and Maxillofacial Surgery, Department of Surgery, Section of Head and Neck Oncologic Surgery and Reconstruction, Mayo Clinic, Mayo College of Medicine, Mail Code: ro_ma_12_12econ, 200 First Street Southwest, Rochester, MN 55905, USA; Department of Oral and Maxillofacial Surgery, Division of Head and Neck Surgery, University of Florida College of Medicine - Jacksonville, 653-1 West 8th Street 2nd FL/LRC, Jacksonville, FL 32209, USA.
² Department of Oral and Maxillofacial Surgery, Division of Head and Neck Surgery, University of Florida College of Medicine - Jacksonville, 653-1 West 8th Street 2nd FL/LRC, Jacksonville, FL 32209, USA; Department of Maxillo-facial, Plastic, Reconstructive and Aesthetic Surgery, Henri Mondor Hospital, 51 avenue du Maréchal de Lattre de Tassigny, Créteil 94010, France.
³ Division of Head and Neck Surgery, Head and Neck Oncologic Surgery and Microvascular Reconstruction Fellowship, Department of Oral and Maxillofacial Surgery, University of Florida College of Medicine - Jacksonville, University of Florida - Jacksonville, 653-1 West 8th Street 2nd FL/LRC, Jacksonville, FL 32209, USA. Electronic address: rui.fernandes@jax.ufl.edu.

PMID: 30454788
DOI: 10.1016/j.coms.2018.08.002

Abstract

Management of oral cavity squamous cell carcinoma has become increasingly driven by emerging evidence as a result of the improved quality of clinical research associating clinicopathologic risk factors with oncologic and survival outcomes. Multiple significant recent changes to treatment guidelines and staging algorithms for oral cavity squamous cell carcinoma reflect evolving understanding of tumor biology and the need for adequately extensive treatment of aggressive disease. This article provides clinicians with a synopsis of the most contemporary management strategies for oral cavity squamous cell carcinoma, framed within the context of historical treatment philosophies.

Keywords: AJCC staging; Anatomic subsite; Depth of invasion; Maxillofacial surgery; NCCN guidelines; Neck dissection; Oral cavity cancer; Squamous cell carcinoma.

Publication types

Review

MeSH terms

Carcinoma, Squamous Cell / pathology
Carcinoma, Squamous Cell / surgery*
Humans
Lymphatic Metastasis
Mouth Neoplasms / pathology
Mouth Neoplasms / surgery*
Neck Dissection
Neoplasm Invasiveness
Neoplasm Staging
Oral Surgical Procedures*
Practice Guidelines as Topic