Infection-Related Glomerulonephritis

Elizabeth A K Hunt; Michael J G Somers

doi:10.1016/j.pcl.2018.08.005

Infection-Related Glomerulonephritis

Pediatr Clin North Am. 2019 Feb;66(1):59-72. doi: 10.1016/j.pcl.2018.08.005.

Authors

Elizabeth A K Hunt¹, Michael J G Somers²

Affiliations

¹ Division of Pediatric Nephrology, University of Vermont Children's Hospital, Larner College of Medicine, UVM Medical Center, 111 Colchester Avenue, Smith 5, Burlington, VT 05405, USA. Electronic address: Liz.hunt@uvmhealth.org.
² Division of Nephrology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.

PMID: 30454751
DOI: 10.1016/j.pcl.2018.08.005

Abstract

Acute postinfectious glomerulonephritis or infection-related glomerulonephritis has been associated with several viral or bacterial infections. Group A beta-hemolytic streptococcal infection is the prototypical cause of postinfectious glomerulonephritis and the main focus of this discussion. The clinical spectrum can vary widely, from asymptomatic microscopic hematuria incidentally detected on routine urinalysis to rapidly progressive glomerulonephritis with acute kidney injury requiring emergent dialysis. Other important causes include glomerulonephritis associated with endocarditis and ventriculoatrial shunt infections. Multiple renal pathologic conditions have been associated with hepatitis B and C infections.

Keywords: Endocarditis; Glomerulonephritis; Hepatitis; Postinfectious; Poststreptococcal; Shunt.

Publication types

Review

MeSH terms

Acute Disease
Bacterial Infections / complications*
Glomerulonephritis / microbiology*
Glomerulonephritis / therapy*
Humans
Risk Factors
Virus Diseases / complications*