Time to First Cigarette and the Risk of Hypertension: A Nationwide Representative Study in Korea

Am J Hypertens. 2019 Jan 15;32(2):202-208. doi: 10.1093/ajh/hpy170.

Abstract

Background: Although previous studies have explored the effect of smoking on blood pressure, little is still known about the role of time to first cigarette (TTFC)-an indicator of nicotine dependence-in hypertension. Therefore, we evaluated this association using representative nationwide data.

Methods: Current daily smokers (N = 941; aged 19-79 years) who participated in the 7th version of the Korea National Health and Nutrition Examination Survey I (2016) were included. We categorized participants into 4 groups according to their TTFC. Furthermore, we categorized participants into hypertensive and nonhypertensive groups based on whether they were taking antihypertensive medications or had high blood pressure (≥140/90 mm Hg). The association of daily TTFC and hypertension was examined without adjusting for any covariates; after adjusting for smoking behaviors; and after adjusting for demographic characteristics, socioeconomic status, health-related behaviors, and comorbidities.

Results: In the fully adjusted weighted regression analysis, participants reporting TTFC ≤ 5 minutes (vs. >60 minutes) had roughly twice the odds of having hypertension (95% confidence interval [CI] = 1.07-4.16) and the adjusted odds ratios compared with TTFC of >60 minutes were 1.53 (95% CI = 0.81-2.86) for 6-30 minutes and 1.31 (95% CI = 0.68-2.50) for 31-60 minutes (Ptrend = 0.03).

Conclusions: Hypertension risk increases with shorter TTFC. Especially, TTFC of ≤5 minutes may prove valuable in assessing the risk of hypertension. Screening smokers based on their TTFC might be useful in assessing their risk of hypertension and smoking cessation programs.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Antihypertensive Agents / therapeutic use
  • Blood Pressure* / drug effects
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hypertension / diagnosis
  • Hypertension / drug therapy
  • Hypertension / epidemiology*
  • Hypertension / physiopathology
  • Male
  • Middle Aged
  • Nutrition Surveys
  • Prognosis
  • Republic of Korea / epidemiology
  • Risk Assessment
  • Risk Factors
  • Smoking / adverse effects*
  • Smoking / epidemiology*
  • Smoking / physiopathology
  • Time Factors
  • Tobacco Use Disorder / diagnosis
  • Tobacco Use Disorder / epidemiology*
  • Tobacco Use Disorder / physiopathology
  • Young Adult

Substances

  • Antihypertensive Agents