Comparative cytotoxic activity between kaempferol and gallic acid against various cancer cell lines

Hong Ngoc Thuy Pham; Jennette A Sakoff; Quan Van Vuong; Michael C Bowyer; Christopher J Scarlett

doi:10.1016/j.dib.2018.10.121

Comparative cytotoxic activity between kaempferol and gallic acid against various cancer cell lines

Data Brief. 2018 Oct 27:21:1033-1036. doi: 10.1016/j.dib.2018.10.121. eCollection 2018 Dec.

Authors

Hong Ngoc Thuy Pham^{1

2}, Jennette A Sakoff³, Quan Van Vuong¹, Michael C Bowyer¹, Christopher J Scarlett¹

Affiliations

¹ School of Environmental and Life Sciences, Faculty of Science, University of Newcastle, Ourimbah, NSW 2258, Australia.
² Faculty of Food Technology, Nha Trang University, No. 2 Nguyen Dinh Chieu Street, Nha Trang City, Khanh Hoa, Vietnam.
³ Department of Medical Oncology, Calvary Mater Newcastle Hospital, Waratah, NSW 2298, Australia.

Abstract

This data article indicates the in vitro cytotoxicity of kaempferol and gallic acid across different cancer cell lines including A2780 (ovarian), H460 (lung), A431 (skin), MIA PaCa-2 (pancreas), Du145 (prostate), HT29 (colon), MCF-7 (breast), BE2-C (neuroblastoma), SJ-G2, U87 and SMA (glioblastoma). The dataset showed that the inhibitory activity of kaempferol was comparatively stronger than gallic acid. Thereby, kaempferol is offered as a potent anticancer agent for further investigation and beneficial as a dietary supplement. The data within this article relates to the research article entitled "Screening phytochemical content, antioxidant, antimicrobial and cytotoxic activities of Catharanthus roseus (L.) G. Don stem extract and its fractions" (Pham et al., 2018).