Spontaneous Coronary Artery Dissection in a Man With a Novel Missense Mutation in SMAD2 Treated by Optical Coherence Tomography-Guided Percutaneous Coronary Intervention

JACC Cardiovasc Interv. 2019 Mar 25;12(6):e45-e47. doi: 10.1016/j.jcin.2018.09.007. Epub 2018 Nov 15.

Authors

Bert Vandeloo¹, Alessia Azzano², Danny Schoors², Aline Verstraeten³, Lut Van Laer³, Bart Loeys³, Paul Vermeersch⁴

Affiliations

¹ Department of Cardiology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium. Electronic address: bert.vandeloo@uzbrussel.be.
² Department of Cardiology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
³ Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
⁴ Department of Cardiology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium; Antwerp Cardiovascular Center, ZNA Middelheim, Antwerp, Belgium.

PMID: 30448172
DOI: 10.1016/j.jcin.2018.09.007

No abstract available

Keywords: Loeys-Dietz Syndrome; SMAD2; optical coherence tomography; percutaneous coronary intervention; spontaneous coronary artery dissection.

Publication types

Case Reports

MeSH terms

Anterior Wall Myocardial Infarction / diagnostic imaging
Anterior Wall Myocardial Infarction / genetics
Anterior Wall Myocardial Infarction / therapy*
Coronary Vessel Anomalies / diagnostic imaging
Coronary Vessel Anomalies / genetics
Coronary Vessel Anomalies / therapy*
Genetic Predisposition to Disease
Humans
Loeys-Dietz Syndrome / diagnosis
Loeys-Dietz Syndrome / genetics*
Male
Middle Aged
Mutation, Missense*
Percutaneous Coronary Intervention*
Predictive Value of Tests
Risk Factors
ST Elevation Myocardial Infarction / diagnostic imaging
ST Elevation Myocardial Infarction / genetics
ST Elevation Myocardial Infarction / therapy*
Smad2 Protein / genetics*
Tomography, Optical Coherence*
Treatment Outcome
Vascular Diseases / congenital*
Vascular Diseases / diagnostic imaging
Vascular Diseases / genetics
Vascular Diseases / therapy
Weight Lifting

Substances

SMAD2 protein, human
Smad2 Protein

Supplementary concepts

Coronary Artery Dissection, Spontaneous