A Contemporary Review of Common Adult Non-germ Cell Tumors of the Testis and Paratestis

Surg Pathol Clin. 2018 Dec;11(4):739-758. doi: 10.1016/j.path.2018.07.002. Epub 2018 Oct 17.

Abstract

This article provides a comprehensive review of non-germ cell tumors of the testis and paratestis in adults, incorporating the latest 2016 World Health Organization updates. Clinical features, gross pathologic findings, key morphologic details, immunohistochemical profiles, and differential diagnoses are covered, with an emphasis on how to resolve commonly encountered, and sometimes difficult, differential diagnoses.

Keywords: Immunohistochemistry; Leydig cell tumor; Non–germ cell tumor; Paratesticular tumor; Sertoli cell tumor; Sex cord–stromal tumor; Testis.

Publication types

  • Review

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Humans
  • Immunohistochemistry
  • Leydig Cell Tumor / diagnosis
  • Leydig Cell Tumor / pathology
  • Lymphoma / diagnosis
  • Lymphoma / pathology
  • Male
  • Sertoli Cell Tumor / diagnosis
  • Sertoli Cell Tumor / pathology
  • Sex Cord-Gonadal Stromal Tumors / diagnosis
  • Sex Cord-Gonadal Stromal Tumors / pathology
  • Testicular Neoplasms / diagnosis
  • Testicular Neoplasms / pathology*
  • Testis / pathology*