Flaviviruses Hit a Moving Target

Cell. 2018 Nov 15;175(5):1175-1176. doi: 10.1016/j.cell.2018.10.060.

Abstract

The enteric nervous system (ENS) is central to intestinal motility and a candidate target for the heterogeneous spectrum of dysmotility diseases. White et al. reveal that relapsing intestinal dysmotility occurs when partial ENS depletion by enteric neurotropic viruses is followed by functional impairment due to intermittent nonspecific intestinal inflammation.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Enteric Nervous System*
  • Flavivirus*
  • Gastrointestinal Motility
  • Humans
  • Intestines
  • Syndrome