Is human fibrin sealant a possible choice for the fixation of laparoscopic inguinal hernia repair? A single center experience and the analysis of the results after 326 TAPP in two years

G Chir. 2018 Sep-Oct;34(5):309-314.

Abstract

Background: Groin hernioplasty is most intervention performed in the worldwide. The present study aimed to evaluate a combination between ultralight mesh and fibrin human sealant in the laparoscopic treatment of inguinal hernia.

Patients and methods: This retrospective study included consecutive patients who underwent laparoscopic transabdominal preperitoneal hernioplasty (TAPP) from 1st of January 2015 to 31st of December 2016. Demographics, surgical data and postoperative outcomes were entered in an anonymized prospective database. Prospective longterm follow-up carried out in all patients.

Results: One hundred eighty-four patients with a median age 57.5 (range 19-84) and median BMI (Body Mass Index) of 28.5 (range 18.5-31.5) were included. A median follow-up of 25 months (median 13-35) was carried out. Five recurrences (1.5%) and two cases of missed lipoma were observed and operated. Chronic pain (CP) was observed in eleven (9%) patients but in 9 patients it decreased spontaneously.

Conclusions: Combination of ultralight mesh and Evicel® in TAPP operation is a safe solution for the treatment of groin hernia. Recurrences and chronic pain are similar to other combination of fibrin sealant and meshes. Moreover action of Evicel® may provide to improve the hemostasis and consequently hematoma of the cord.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Drug Evaluation
  • Female
  • Fibrin Tissue Adhesive / therapeutic use*
  • Follow-Up Studies
  • Hematoma / etiology
  • Hernia, Inguinal / surgery*
  • Herniorrhaphy / methods*
  • Humans
  • Laparoscopy / methods*
  • Male
  • Middle Aged
  • Pain, Postoperative / etiology
  • Recurrence
  • Retrospective Studies
  • Surgical Mesh
  • Tissue Adhesives / therapeutic use*
  • Young Adult

Substances

  • Fibrin Tissue Adhesive
  • Tissue Adhesives