The Unprecedented Role of Gold Nanomaterial in Diabetes Management

Recent Pat Drug Deliv Formul. 2019;13(3):219-227. doi: 10.2174/1871526518666181114165352.

Abstract

Gold nanoparticles possess unique mechanical, chemical, photo-optical and biological properties and have been an interesting field of research on life sciences. The research studies produced new nanodevices and nanotechnology-based biosensing, diagnostics therapeutics, and targeted drug delivery systems. In this review, the unique potential aspects of gold nanoparticles/ nanoformulations/ or devices related to diabetes management have been discussed together with the recent patent on the gold nanoparticles developed for diabetes management. The first part of this review will focus on recent strategies for the treatment of hyperglycemia and its management with the help of gold nanoparticles and the second part of the review focused on recent patents on gold nanoparticles useful in the diabetes management. Gold nanoparticles have proved themselves useful in diabetes therapeutics and diagnostics. Due to the high surface area, and low toxicity, gold nanoparticles have become a unique aspect of the delivery approach. The main issues that need to be covered are the biopharmaceutics, biocompatibility, and potential clinical applications.

Keywords: Gold nanoparticles; diabetes; gene delivery; nanodevices; nanomedicine; patents..

Publication types

  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus / diagnosis
  • Diabetes Mellitus / drug therapy*
  • Drug Delivery Systems*
  • Gold / chemistry
  • Humans
  • Hyperglycemia / drug therapy
  • Hypoglycemic Agents / administration & dosage
  • Metal Nanoparticles*
  • Nanotechnology
  • Patents as Topic

Substances

  • Hypoglycemic Agents
  • Gold