Successful therapy with secukinumab in a patient with generalized pustular psoriasis carrying homozygous IL36RN p.His32Arg mutation

Int J Dermatol. 2019 Jan;58(1):e16-e17. doi: 10.1111/ijd.14293. Epub 2018 Nov 14.

Authors

Romain Gabeff^{1

2}, Roba Safar¹, Sophie Leducq¹, Annabel Maruani¹, Guillaume Sarrabay³, Isabelle Touitou³, Mahtab Samimi^{1

4}

Affiliations

¹ Department of Dermatology, University Hospital of Tours, University François-Rabelais, Tours, France.
² Department of Dermatology, County Hospital, La Roche Sur Yon, France.
³ Laboratory of Rare and Autoinflammatory Diseases, University Hospital, INSERM U1183, Montpellier, France.
⁴ ISP1282 INRA, University of Tours, Tours, France.

PMID: 30430544
DOI: 10.1111/ijd.14293

No abstract available

Publication types

Letter

MeSH terms

Adolescent
Adult
Antibodies, Monoclonal / therapeutic use*
Antibodies, Monoclonal, Humanized
Child, Preschool
Female
Homozygote
Humans
Interleukins / genetics*
Male
Middle Aged
Mutation
Psoriasis / drug therapy*
Psoriasis / genetics
Treatment Outcome

Substances

Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
IL36RN protein, human
Interleukins
secukinumab