An update on antimicrobial resistance and the role of newer antimicrobial agents for Pseudomonas aeruginosa

Indian J Med Microbiol. 2018 Jul-Sep;36(3):303-316. doi: 10.4103/ijmm.IJMM_18_334.

Abstract

Infections due to Pseudomonas aeruginosa is a major health concern, especially hospital-acquired infections, in critically ill individuals. Antimicrobial resistance (AMR) increases the morbidity and mortality rates associated with pseudomonal infections. In this review, we aim to address two major aspects of P. aeruginosa. The first part of the review will focus on the burden of AMR and its prevailing mechanisms seen in India, while the second part will focus on the challenges and approaches in the management with special emphasis on the role of newer antimicrobial agents.

Keywords: Antimicrobial resistance; India; Pseudomonas aeruginosa; newer antimicrobials; treatment.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / pharmacology*
  • Anti-Infective Agents / therapeutic use*
  • Disease Management
  • Drug Resistance, Bacterial*
  • Humans
  • India / epidemiology
  • Prevalence
  • Pseudomonas Infections / drug therapy*
  • Pseudomonas Infections / epidemiology
  • Pseudomonas Infections / microbiology*
  • Pseudomonas aeruginosa / drug effects*

Substances

  • Anti-Infective Agents