Pharmacist-Initiated Management of a Suspected Case of Risperidone-Induced Neuroleptic Malignant Syndrome in an Aged-Care Resident. The Role of Residential Medication Management Reviews in Medication Safety

J Pharm Pract. 2020 Jun;33(3):382-385. doi: 10.1177/0897190018806414. Epub 2018 Nov 14.

Abstract

A 70-year-old female aged-care resident was referred by her general practitioner for a residential medication management review after nurses reported difficulties with swallowing, episodes of hyperthermia, elevated blood pressure, and tachycardia. These symptoms were accompanied by increasing confusion and drowsiness. Risperidone had recently been prescribed to treat behavioral and psychological symptoms of dementia. This case study describes the pharmacist-initiated management of the symptoms through a national medication review program. It demonstrates the valuable role collaborative medication reviews play in managing adverse drug reactions in aged-care.

Keywords: adverse drug reaction; aged-care; long-term care; neuroleptic malignant syndrome or NMS and medication review.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antipsychotic Agents / adverse effects
  • Female
  • Humans
  • Medication Therapy Management
  • Neuroleptic Malignant Syndrome* / diagnosis
  • Neuroleptic Malignant Syndrome* / drug therapy
  • Neuroleptic Malignant Syndrome* / etiology
  • Pharmacists
  • Risperidone / adverse effects

Substances

  • Antipsychotic Agents
  • Risperidone