Recent Advances in Experimental Allergy

Int Arch Allergy Immunol. 2018;177(4):281-289. doi: 10.1159/000494440. Epub 2018 Nov 13.

Abstract

Atopic disorders are on the rise and pose a great burden on society. A better understanding of the underlying mechanisms is required for the development of improved or novel therapeutic strategies. Here we aim to highlight recent advances in experimental allergy, with a particular focus on proposed treatment alternatives for airway disorders, atopic dermatitis, and food allergy. Furthermore, we discuss recent work focusing on molecular and cellular mechanisms that might offer candidates for future preventive or therapeutic intervention.

Keywords: Allergy; Atopic disorders; Immunomodulation; Inflammatory mechanisms.

Publication types

  • Review

MeSH terms

  • Animals
  • Dermatitis, Atopic / immunology*
  • Dermatitis, Atopic / therapy
  • Food Hypersensitivity / immunology*
  • Food Hypersensitivity / therapy
  • Humans
  • Immunomodulation
  • Inflammation
  • Models, Animal
  • Respiratory Mucosa