Strong antibacterial dental resin composites containing cellulose nanocrystal/zinc oxide nanohybrids

Yazi Wang; Hongfei Hua; Wei Li; Ruili Wang; Xiaoze Jiang; Meifang Zhu

doi:10.1016/j.jdent.2018.11.002

Strong antibacterial dental resin composites containing cellulose nanocrystal/zinc oxide nanohybrids

J Dent. 2019 Jan:80:23-29. doi: 10.1016/j.jdent.2018.11.002. Epub 2018 Nov 10.

Authors

Yazi Wang¹, Hongfei Hua², Wei Li¹, Ruili Wang¹, Xiaoze Jiang¹, Meifang Zhu³

Affiliations

¹ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China.
² Department of Oral Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Key Laboratory of Stomatology, National Clinical Research Center of Stomatology, Shanghai 200011, China.
³ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China. Electronic address: zhumf@dhu.edu.cn.

PMID: 30423354
DOI: 10.1016/j.jdent.2018.11.002

Abstract

Objective: The aim is to explore the reinforcing and antibacterial effect of cellulose nanocrystal/zinc oxide (CNC/ZnO) nanohybrids on dental resin composites (DRCs).

Methods: CNC/ZnO nanohybrids were prepared through precipitating Zn²⁺ on the surface of CNC and then introduced into the DRCs. The mechanical properties of DRCs including compressive strength, flexural modulus, flexural strength, and Vickers microhardness were characterized. The antibacterial activity of DRCs to Streptococcus mutans was determined and the morphology of Streptococcus mutans on the surface of DRCs after incubation was observed. The morphology of fractured surface after flexural test and Zn content in DRCs were analyzed.

Results: Compared with DRCs without CNC/ZnO nanohybrids, DRCs containing 2 wt.% CNC/ZnO nanohybrids possess higher compressive strength and flexural modulus and there is no significantly statistical difference (P＞0.05) on the flexural strength and Vickers microhardness. The excess use of CNC/ZnO nanohybrids decreases the mechanical properties of DRCs except flexural modulus. DRCs containing CNC/ZnO nanohybrids show excellent antibacterial properties and a 78% reduction in bacterial number is obtained when 2% CNC/ZnO nanohybrids are added.

Conclusion: The small amounts of CNC/ZnO nanohybrids have a positive influence on the mechanical and antibacterial properties of DRCs.

Significance: The prepared DRCs are promising to address bulk fracture and secondary caries.

Keywords: Bacteria; Caries; Composite materials; Mechanical properties; Streptococcus mutans; ZnO.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents*
Cellulose*
Composite Resins*
Materials Testing
Nanoparticles*
Streptococcus mutans
Zinc Oxide*

Substances

Anti-Bacterial Agents
Composite Resins
Cellulose
Zinc Oxide