Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling

Gregory E Amidon; Bradley D Anderson; Joseph P Balthasar; Christel A S Bergstrom; Shiew-Mei Huang; Gerald Kasting; Filippos Kesisoglou; Johannes G Khinast; Donald E Mager; Christopher J Roberts; Lian Yu

doi:10.1016/j.xphs.2018.11.002

Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling

J Pharm Sci. 2019 Jan;108(1):2-7. doi: 10.1016/j.xphs.2018.11.002. Epub 2018 Nov 10.

Affiliations

¹ University of Michigan, Ann Arbor, Michigan 48109. Electronic address: geamidon@umich.edu.
² University of Kentucky, Lexington, Kentucky 40506.
³ University at Buffalo, State University of New York, Buffalo, New York 14260.
⁴ Uppsala University, Uppsala, Sweden.
⁵ Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993.
⁶ University of Cincinnati, Cincinnati, Ohio 45220.
⁷ Merck & Co., Inc., Kenilworth, New Jersey 07033.
⁸ Institute for Process and Particle Engineering, Graz University of Technology, Graz, Austria.
⁹ University of Delaware, Newark, Delaware 19716.
¹⁰ University of Wisconsin, Madison, Wisconsin 53706.

PMID: 30423338
DOI: 10.1016/j.xphs.2018.11.002

Abstract

With this issue of the Journal of Pharmaceutical Sciences, we celebrate the nearly 6 decades of contributions to mechanistic-based modeling and computational pharmaceutical sciences. Along with its predecessor, The Journal of the American Pharmaceutical Association: Scientific Edition first published in 1911, JPharmSci has been a leader in the advancement of pharmaceutical sciences beginning with its inaugural edition in 1961. As one of the first scientific journals focusing on pharmaceutical sciences, JPharmSci has established a reputation for publishing high-quality research articles using computational methods and mechanism-based modeling. The journal's publication record is remarkable. With over 15,000 articles, 3000 notes, and more than 650 reviews from industry, academia, and regulatory agencies around the world, JPharmSci has truly been the leader in advancing pharmaceutical sciences.

Keywords: absorption, distribution, metabolism, and excretion (ADME); biophysical model(s); in silico modeling; in vitro model(s); mathematical model(s); mechanistic modeling; molecular modeling; pharmacokinetic-pharmacodynamic (PKPD) modeling; physiologically based pharmacokinetic (PBPK) modeling.

MeSH terms

Biopharmaceutics / methods*
Computational Biology / methods*
Drug Industry / methods
Humans
Publishing