Pediatric Musculoskeletal Imaging: The Indications for and Applications of PET/Computed Tomography

Hedieh Khalatbari; Marguerite T Parisi; Neha Kwatra; Douglas J Harrison; Barry L Shulkin

doi:10.1016/j.cpet.2018.08.008

Pediatric Musculoskeletal Imaging: The Indications for and Applications of PET/Computed Tomography

PET Clin. 2019 Jan;14(1):145-174. doi: 10.1016/j.cpet.2018.08.008. Epub 2018 Oct 24.

Authors

Hedieh Khalatbari¹, Marguerite T Parisi², Neha Kwatra³, Douglas J Harrison⁴, Barry L Shulkin⁵

Affiliations

¹ Department of Radiology, University of Washington School of Medicine, Seattle Children's Hospital, 4800 Sandpoint Way NE, Seattle, WA 98105, USA. Electronic address: Hedieh.khalatbari@seattlechildrens.org.
² Department of Radiology, University of Washington School of Medicine, Seattle Children's Hospital, 4800 Sandpoint Way NE, Seattle, WA 98105, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle Children's Hospital, 4800 Sandpoint Way NE, Seattle, WA 98105, USA.
³ Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
⁴ Department of Pediatrics, MD Anderson Cancer Center, 7600 Beechnut Street, Houston, TX 77074, USA.
⁵ Department of Diagnostic Imaging, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

PMID: 30420216
DOI: 10.1016/j.cpet.2018.08.008

Abstract

The use of PET/computed tomography (CT) for the evaluation and management of children, adolescents, and young adults continues to expand. The principal tracer used is 18F-fluorodeoxyglucose and the principal indication is oncology, particularly musculoskeletal neoplasms. The purpose of this article is to review the common applications of PET/CT for imaging of musculoskeletal issues in pediatrics and to introduce the use of PET/CT for nononcologic issues, such as infectious/inflammatory disorders, and review the use of 18F-sodium fluoride in trauma and sports-related injuries.

Keywords: 18F; FDG; Musculoskeletal; PET/CT; Pediatric.

Publication types

Review

MeSH terms

Child
Humans
Musculoskeletal Diseases / diagnostic imaging*
Musculoskeletal System / diagnostic imaging
Pediatrics / methods*
Positron Emission Tomography Computed Tomography / methods*