An unusual presentation of metastatic malignant melanoma causing jejuno-jejunal intussusception: a case report

J Med Case Rep. 2018 Nov 13;12(1):337. doi: 10.1186/s13256-018-1887-5.

Abstract

Background: Small bowel intussusception in adults is rarely encountered. In most cases small bowel intussusception is caused by benign neoplastic lesions, but metastasis of cutaneous malignant melanoma causing small bowel intussusception is rare. We present such a case of jejuno-jejunal intussusception with an intraluminal metastatic lesion acting as a lead point.

Case presentation: We present a case of a 71-year-old Caucasian man who presented with small bowel obstruction. His medical history revealed that he had had a cutaneous malignant melanoma excised 7 years earlier and underwent total laryngectomy due to a metastasis 6 years later. The disease was classified as stage IV and he was receiving immunotherapy. An emergency abdominal computed tomography scan demonstrated small bowel obstruction, most probably caused by an intraluminal lesion. An emergency laparotomy revealed an intraluminal metastatic lesion causing jejuno-jejunal intussusception. Metastasectomy of the lesion was performed and 13 days later he was discharged.

Conclusions: Jejuno-jejunal intussusception with a malignant melanoma metastasis acting as a lead point is very rare. With the gastrointestinal tract being a common location of distal metastases, a medical history of malignant melanoma treatment in cases of small bowel obstruction should raise a suspicion of possible metastatic disease. A computed tomography scan is the diagnostic modality of choice and surgery still remains the standard of care.

Keywords: Emergency surgery; Gastrointestinal metastasis; Jejuno-jejunal intussusception; Malignant melanoma; Metastasectomy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Humans
  • Intestinal Obstruction / diagnostic imaging*
  • Intestinal Obstruction / etiology
  • Intestinal Obstruction / surgery
  • Intussusception / drug therapy*
  • Intussusception / etiology
  • Intussusception / surgery
  • Jejunal Neoplasms / diagnostic imaging*
  • Jejunal Neoplasms / secondary
  • Jejunal Neoplasms / surgery
  • Laparotomy*
  • Male
  • Melanoma / complications
  • Melanoma / drug therapy*
  • Melanoma / pathology
  • Melanoma, Cutaneous Malignant
  • Metastasectomy
  • Skin Neoplasms / complications
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / pathology
  • Tomography, X-Ray Computed*
  • Treatment Outcome