Two new chromene derivatives from Artemisia songarica

J Asian Nat Prod Res. 2018 Oct;20(10):943-950. doi: 10.1080/10286020.2018.1497017. Epub 2018 Nov 11.

Abstract

Two new chromene derivatives, songaricachromenes A (1) and B (2), were isolated from Artemisia songarica, along with 10 known compounds (3-12). The structures and stereochemistry of the new compounds were elucidated by analyses of the NMR, MS, and electronic circular dichroism (ECD) data. All the isolates (1-12) were evaluated for their NO inhibitory effects on LPS-stimulated BV-2 microglial cells.

Keywords: Compositae;; NO inhibition; chromene.

MeSH terms

  • Artemisia / chemistry*
  • Benzopyrans / chemistry
  • Benzopyrans / isolation & purification*
  • Magnetic Resonance Spectroscopy
  • Nitric Oxide / antagonists & inhibitors

Substances

  • Benzopyrans
  • Nitric Oxide