Visible-Light Photocatalysis of the Ketyl Radical Coupling Reaction

Qing Xia; Jianyang Dong; Hongjian Song; Qingmin Wang

doi:10.1002/chem.201804873

Visible-Light Photocatalysis of the Ketyl Radical Coupling Reaction

Chemistry. 2019 Feb 26;25(12):2949-2961. doi: 10.1002/chem.201804873. Epub 2018 Dec 14.

Authors

Qing Xia¹, Jianyang Dong¹, Hongjian Song¹, Qingmin Wang^{1

2}

Affiliations

¹ State Key Laboratory of Elemento-Organic Chemistry, Research Institute of, Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, 300071, P. R. China.
² Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, 300071, P. R. China.

PMID: 30414339
DOI: 10.1002/chem.201804873

Abstract

Ketyl radical coupling reactions for the construction of diversely functionalized alcohols have been continuously developed for many decades. Based on the recently widespread application of photocatalysis, ketyl radical coupling reactions have also witnessed rapid development. This Minireview aims to briefly and concisely summarize the methods to construct ketyl radical intermediates through visible-light photocatalysis over the past 10 years. The ketyl-radical-generation activators are grouped as Lewis acids, Brønsted acids, in situ generated Brønsted acids, and others.

Keywords: coupling reactions; electron transfer; ketyl radical; photocatalysis; radical reactions.

Publication types

Review