1 Department of Biology and Department of Cell Biology, Duke University and Duke University Medical School, French Family Science Center, 124 Science Drive, Box 90338, Durham, NC, 27708-0338, USA. dkiehart@duke.edu.
2 Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, CB 8231, 660 South Euclid Ave., Saint Louis, MO, 63110, USA. jacooper@wustl.edu.
We describe our search for the molecular mechanisms of cell motility with personal recollections of bucket biochemistry in Tom Pollards Lab at the Johns Hopkins, circa 1980.