Abstract
Key cycle changes occur as women transition from reproductive life to menopause, and they can be roughly linked to menopausal staging. It is important to understand the types of studies that inform the current knowledge. Patterns of symptoms within menstrual cycles (sleep, headache) generally favor worsening in association with the perimenstrual phase of the cycle, and patterns of chronic symptoms, such as hot flashes and adverse mood, appear to be worse when hormones are more variable.
Keywords:
Folliculogenesis; Gonadotropins; Perimenopause; Reproductive aging.
Copyright © 2018 Elsevier Inc. All rights reserved.
MeSH terms
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Aging / metabolism*
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Aging / physiology
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Anti-Mullerian Hormone / metabolism
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Biomarkers / metabolism
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Depression
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Estradiol / metabolism
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Female
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Follicle Stimulating Hormone / metabolism
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Hot Flashes
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Humans
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Inhibins / metabolism
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Irritable Mood
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Longitudinal Studies
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Luteinizing Hormone / metabolism
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Menopause / metabolism*
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Menopause / physiology
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Menstrual Cycle / metabolism*
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Menstrual Cycle / physiology
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Progesterone / metabolism
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Reproductive Health*
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Sleep Wake Disorders
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Women's Health*
Substances
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Biomarkers
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Progesterone
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Estradiol
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Inhibins
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Anti-Mullerian Hormone
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Luteinizing Hormone
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Follicle Stimulating Hormone