Abstract
An expression system for the synthesis of early antigenic proteins HPV16 E2, HPV16 E6, and HPV16 E7 of high-risk papillomavirus based on transgenic tomato fruits was developed. It is planned to use the early antigenic proteins synthesized to create a therapeutic vaccine against cervical cancer.
MeSH terms
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Antigens / chemistry
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Antigens / genetics
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Blotting, Western
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DNA-Binding Proteins / genetics*
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Enzyme-Linked Immunosorbent Assay
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Escherichia coli / genetics
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Oncogene Proteins, Viral / genetics*
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Papillomavirus E7 Proteins / genetics*
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Plant Proteins / metabolism*
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Plants, Genetically Modified / genetics
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Plants, Genetically Modified / metabolism
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Repressor Proteins / genetics*
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Solanum lycopersicum
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Transcriptome
Substances
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Antigens
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DNA-Binding Proteins
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E2 protein, Human papillomavirus type 16
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E6 protein, Human papillomavirus type 16
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Oncogene Proteins, Viral
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Papillomavirus E7 Proteins
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Plant Proteins
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Repressor Proteins
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oncogene protein E7, Human papillomavirus type 16