Mild cognitive impairment in primary care: a clinical review

Postgrad Med J. 2018 Nov;94(1117):647-652. doi: 10.1136/postgradmedj-2018-136035. Epub 2018 Nov 5.

Abstract

Dementia is projected to become a global health priority but often not diagnosed in its earlier preclinical stage which is mild cognitive impairment (MCI). MCI is generally referred as a transition state between normal cognition and Alzheimer's disease. Primary care physicians play an important role in its early diagnosis and identification of patients most likely to progress to Alzheimer's disease while offering evidenced-based interventions that may reverse or halt the progression to further cognitive impairment. The aim of this review is to introduce the concept of MCI in primary care through a case-based clinical review. We discuss the case of a patient with MCI and provide an evidence-based framework for assessment, early recognition and management of MCI while addressing associated risk factors, neuropsychiatric symptoms and prognosis.

Keywords: dementia; mild cognitive impairment; primary care; short-term memory loss.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Alzheimer Disease
  • Cognitive Dysfunction / diagnosis*
  • Cognitive Dysfunction / physiopathology
  • Cognitive Dysfunction / psychology
  • Disease Progression
  • Early Diagnosis
  • Educational Status
  • Evidence-Based Practice / methods*
  • Humans
  • Male
  • Medical History Taking
  • Neuropsychological Tests
  • Predictive Value of Tests
  • Primary Health Care*