Objective: The purpose of this study was to explore the relationship between maternal tea consumption and birth outcomes. Methods: From January 2005 to December 2010, pregnant women were recruited from Nanjing Maternity and Child Health Hospital. The basic information and the situation of tea consumption during pregnancy were investigated using questionnaire and the birth outcomes of newborns were followed up. Finally, 500 pairs of mothers and infants with complete and standard-compliant data were included in the analysis. The differences of birth outcomes between the tea consumption group and the non tea consumption group were compared and the associations between tea consumption and birth outcomes were analyzed using multivariate logistic regression. Results: Mother's tea consumption rate was 32.8% (164 cases) during pregnancy. The rate of low birth weight in the tea consumption group was (5.5%, 9 cases) and higher than that in the non-tea consumption group (2.1%, 7 cases) (P=0.042). There was no significant difference in the rate of premature birth, small for gestational age, fetal distress, and macrosomia between the two groups After the adjustment of maternal age, education level, family income, weight gain during pregnancy, pre-pregnancy BMI, parity, gestational hypertension, gestational diabetes, neonatal gender and gestational age, compared with non-tea consumption group, there was a positive effect on low birth weight, OR(95%CI) was 4.76 (1.06-21.48). The OR (95%CI) value of the low birth weight risk of the tea group was 5.30 (1.04-26.92) compared with the non-tea consumption group after the adjustment of additional factors such as passive smoking, coffee consumption, folic acid supplement, mineral supplement, carbonated beverage consumption. Simultaneously, compared with non-tea consumption group, there was no statistically significant association between tea consumption during pregnancy and premature birth, small for gestational age, fetal distress and macrosomia (P>0.05). Conclusion: Tea consumption during pregnancy was a risk factor for low birth weight in offspring.
目的： 探索妊娠期饮茶与子代出生结局的关系。 方法： 于2005年1月至2010年12月在南京市妇幼保健院招募孕妇，问卷调查基本信息及妊娠期饮茶情况，随访分娩期新生儿出生结局。最终将资料完整且符合标准的500对母婴纳入分析。比较饮茶组与非饮茶组子代出生结局差异，采用多因素logistic回归模型分析妊娠期饮茶与子代出生结局的关联。 结果： 妊娠期饮茶率为32.8%（164名）；饮茶组新生儿低出生体重检出率[5.5%（9例）]高于非饮茶组[2.1%（7例）]（P=0.042）；两组早产、小于胎龄儿、胎儿窘迫、巨大儿检出率差异均无统计学意义（P值均>0.05）。调整母亲年龄、受教育水平、家庭人均年收入、妊娠期体重增加、孕前BMI、产次、妊娠期高血压疾病、妊娠期糖尿病、新生儿性别、孕周等因素后，与非饮茶组比，饮茶组发生低出生体重的OR(95%CI）值为4.76(1.06~21.48)；增加调整被动吸烟、饮咖啡、叶酸补充、矿物质补充、碳酸饮料饮用等因素后，与非饮茶组比，饮茶组发生低出生体重的OR(95%CI）值为5.30 (1.04~26.92)。妊娠期饮茶与新生儿早产、小于胎龄儿、胎儿窘迫和巨大儿关联均无统计学意义（P>0.05）。 结论： 妊娠期饮茶是子代低出生体重发生的危险因素。.
Keywords: Birth weight; Cohort studies; Pregnant women; Tea.