[Minimal invasive surgery in the treatment of neuroendocrine tumors of the pancreas]

Zhonghua Wai Ke Za Zhi. 2018 Nov 1;56(11):877-880. doi: 10.3760/cma.j.issn.0529-5815.2018.11.019.
[Article in Chinese]

Abstract

Neuroendocrine tumor of the pancreas (pNET) is a rare group of neoplasms with widely heterogeneity. Complete surgical resection remains the only potentially curative treatment for pNET. Compared to open surgery, minimal invasive approach treating pNET could decrease bleeding and shorten postoperative hospital stay, while didn't show difference in operation time, postoperative complication rate and overall mortality. Therapeutic strategy was formulated by synthesizing clinical symptoms, tumor size and tumor stage. Minimal invasive approach can achieve radical curve of oncology and provide refine manipulation condition to improve surgical safety and efficacy, meanwhile realize function preservation. Minimal invasive approach is a safe and efficient method in treating pNET, but further prospective, randomized control trials are required.

胰腺神经内分泌肿瘤是罕见的异质性肿瘤,手术切除是唯一可能治愈的方式。微创技术治疗胰腺神经内分泌肿瘤术中出血量少、术后住院时间短,在手术时间、术后并发症发生率及总体病死率等方面与开放手术相比无差异。治疗策略需要综合临床症状、肿瘤大小、肿瘤分级分期等信息制定。微创技术既能达到肿瘤学根治,也能为术者提供精细操作的条件,提高手术的安全性和有效性,并实现器官功能保留,是治疗胰腺神经内分泌肿瘤安全可行的手段,但仍需要前瞻性随机对照研究结果进一步证实。.

Keywords: Laparoscopic surgery; Neuroendocrine tumors; Pancreatic neoplasms; Robotic surgery.

MeSH terms

  • Humans
  • Laparoscopy
  • Minimally Invasive Surgical Procedures* / methods
  • Neuroendocrine Tumors* / surgery
  • Pancreatectomy* / methods
  • Pancreatic Neoplasms* / surgery
  • Treatment Outcome