In-phantom neutron dose measurement using Gafchromic film dosimeter for QA of BNCT beams

Appl Radiat Isot. 2019 Jan:143:79-86. doi: 10.1016/j.apradiso.2018.09.030. Epub 2018 Oct 27.

Abstract

In order to improve the quality assurance (QA) procedure for beams of boron neutron capture therapy (BNCT), this study introduced using the Gafchromic film dosimeter for neutron dose measurement of BNCT beams. The crucial part of this study was investigating an approach to employ the Gafchromic film dosimeter placed inside a PMMA phantom irradiated by a BNCT beam. The spatial distribution of neutron dose of the film was determined using measurements and Monte Carlo calculations. By employing the present approach, the two-dimensional distributions of the neutron dose component of the film at specific depths in the phantom were successfully obtained. The determined neutron dose profiles were in good agreement with the calculated ones. This study also confirmed the finding that the film dosimeter is sensitive to thermal neutrons by comparing the depth-capture-reaction-rate and depth-dose distributions. Results of this work not only proved the feasibility of using the proposed method for the QA measurement of beam delivery but also revealed the advantages of easy-handling and remarkable spatial resolution of the film dosimeter when applied to BNCT fields. The present work can help to verify the dose uniformity and output stability of BNCT beams prior to clinical irradiation.

Keywords: BNCT; Gafchromic film dosimeter; Quality assurance; Two-dimensional distribution.

MeSH terms

  • Boron Neutron Capture Therapy / standards*
  • Calibration
  • Film Dosimetry / methods*
  • Film Dosimetry / statistics & numerical data
  • Gamma Rays
  • Humans
  • Monte Carlo Method
  • Neutrons
  • Phantoms, Imaging
  • Polymethyl Methacrylate
  • Quality Assurance, Health Care
  • Radiotherapy Dosage

Substances

  • Polymethyl Methacrylate