This article describes a clinical experience in a 7-year-old girl with chronic spontaneous urticaria and atopic dermatitis, resistant to therapy with antihistamines and topical steroid. Omalizumab treatment not only allowed complete remission of chronic spontaneous urticaria but also significantly improved atopic dermatitis symptoms. The off-label use of omalizumab was well tolerated and no adverse events were reported.
Keywords: Chronic urticaria; atopic dermatitis; omalizumab.