Investigation of elevation as a risk factor for hypertensive disorders of pregnancy among Colorado women between 2007 and 2015

Hypertens Pregnancy. 2019 Feb;38(1):1-12. doi: 10.1080/10641955.2018.1538378. Epub 2018 Nov 1.

Abstract

Objective: The purpose of this study is to determine the association between high elevation and hypertensive disorders of pregnancy (HDP).

Methods: Retrospective cohort study using Colorado birth certificate data to compare HDP at high (≥8,000 ft), moderate (4,501-7,999 ft), or low (≤4,500 ft) elevation using logistic regression.

Results: Among the cohort (n = 314,431), 3.4% of women developed a HDP. High or moderate elevation was not significantly associated with HDP relative to low elevation (adjusted odds ratio [aOR] 1.16, 95% confidence interval [CI] 0.93-1.43; aOR 1.14, 95% CI 0.98-1.31, respectively).

Conclusion: Women living at high or moderate elevation do not have higher odds of HDP.

Keywords: Altitude; hypertensive disorders of pregnancy; population health; pregnancy.

Publication types

  • Retracted Publication

MeSH terms

  • Adolescent
  • Adult
  • Altitude*
  • Child
  • Colorado
  • Databases, Factual
  • Female
  • Humans
  • Hypertension, Pregnancy-Induced / etiology*
  • Middle Aged
  • Pregnancy
  • Retrospective Studies
  • Risk Factors
  • Young Adult