Psychology of Chronic Pelvic Pain: Prevalence, Neurobiological Vulnerabilities, and Treatment

Clin Obstet Gynecol. 2019 Mar;62(1):22-36. doi: 10.1097/GRF.0000000000000412.

Abstract

Patients with pelvic pain suffer from psychological conditions at a disproportionately high rate compared with their peers. We review environmental, genetic, inflammatory, and neurobiological factors that increase vulnerability to developing both of these conditions. We review treatment strategies for chronic pelvic pain in patients who have comorbid psychological conditions, including both nonpharmacologic and pharmacologic options.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Antidepressive Agents, Tricyclic / pharmacology
  • Anxiety / complications*
  • Catastrophization / complications*
  • Chronic Pain / complications
  • Chronic Pain / drug therapy
  • Chronic Pain / psychology*
  • Chronic Pain / therapy
  • Cognitive Behavioral Therapy
  • Depression / complications*
  • Female
  • Gabapentin / pharmacology
  • Gabapentin / therapeutic use
  • Humans
  • Off-Label Use
  • Pelvic Pain / complications
  • Pelvic Pain / drug therapy
  • Pelvic Pain / psychology*
  • Pelvic Pain / therapy
  • Prevalence
  • Serotonin and Noradrenaline Reuptake Inhibitors / pharmacology
  • Serotonin and Noradrenaline Reuptake Inhibitors / therapeutic use
  • Twin Studies as Topic

Substances

  • Antidepressive Agents, Tricyclic
  • Serotonin and Noradrenaline Reuptake Inhibitors
  • Gabapentin