Polyunsaturated fatty acids (PUFAs) are important for human health. They are traditionally extracted from animals and plants but can be alternatively derived from oleaginous microbes, and engineering microbial metabolism can improve PUFA accumulation. The next frontier is to engineer more efficient PUFA-producing microbes using systems and synthetic biology tools.
Keywords: lipids; metabolic engineering; oleaginous microbes; polyunsaturated fatty acids.
Copyright © 2018 Elsevier Ltd. All rights reserved.