[Erythropoietin and blood loss in selected orthopedic procedures]

Pol Merkur Lekarski. 2018 Oct 29;45(268):141-149.
[Article in Polish]

Abstract

Orthopedic surgical procedures, especially in the lower limbs, are associated with a high risk of massive bleeding and, consequently, the development of anemia and the need for blood transfusions and its preparations. This creates the need to look for effective methods of prevention and treatment of anemia that will be safe for the patient and reduce the cost of treatment. One of the most common methods of limiting the allogenic blood usage in orthopedic procedures is the use of autologus transfusions. In addition to many benefits, they may contribute to the patient's anemia, which is a serious health problem in the post-operative period. Analyzed data from the literature indicate that the use of recombinant human erythropoietin significantly reduces the need for blood transfusion in the perioperative period and may reduce the cost of treatment.

Keywords: anemia; blood transfusion; erythropoietin; orthopedic procedures.

Publication types

  • Editorial
  • Review

MeSH terms

  • Anemia / drug therapy
  • Anemia / etiology*
  • Erythropoietin / therapeutic use*
  • Hemorrhage / complications
  • Hemorrhage / etiology*
  • Humans
  • Orthopedic Procedures / adverse effects*
  • Orthopedic Procedures / economics
  • Perioperative Period
  • Recombinant Proteins / therapeutic use

Substances

  • EPO protein, human
  • Recombinant Proteins
  • Erythropoietin