Diagnostic histochemistry of soft tissue lesions

Semin Diagn Pathol. 2018 Nov;35(6):399-406. doi: 10.1053/j.semdp.2018.10.005. Epub 2018 Oct 16.

Abstract

Histochemical methods (HM) were, at one time, extensively used in all facets of anatomic pathology, including analysis of soft tissue lesions. That situation has changed with the advent of other adjunctive procedures, but HM still do contribute meaningfully to the evaluation of several tumefactive conditions in the soft tissue. This brief review considers selected neoplastic, quasineoplastic, and pseudoneoplastic lesions in that category, with emphasis on their histochemical properties.

Keywords: Histochemistry; Mucin stains; Periodic acid-Schiff stains; Soft tissue lesions; Trichrome stains.

Publication types

  • Review

MeSH terms

  • Biopsy
  • Connective Tissue / pathology*
  • Connective Tissue Diseases / pathology*
  • Histocytochemistry*
  • Humans
  • Predictive Value of Tests
  • Prognosis
  • Soft Tissue Neoplasms / pathology*
  • Staining and Labeling