Factors Associated with Nonfatal Overdose During a Public Health Emergency

Subst Use Misuse. 2019;54(1):39-45. doi: 10.1080/10826084.2018.1491051. Epub 2018 Oct 26.

Abstract

Background: In 2016, in the Canadian province of British Columbia, the Provincial Health Officer declared drug-related overdose deaths a public health emergency.

Objectives: In this study, we examine factors associated with recent non-fatal overdose during a time of unprecedented rates of overdose and increasing involvement of fentanyl and fentanyl derivatives in overdose deaths.

Methods: Between June and September 2016, a cross-sectional survey was conducted among people who inject drugs (PWID) in Victoria, British Columbia, Canada. Bivariable and multivariable logistic regression analyses were used to examine factors associated with recent non-fatal overdose.

Results: A total of 187 PWID were included in the present study, of whom 56 (29.9%) reported having overdosed in the previous 6 months. In multivariable analyses, fentanyl injection (Adjusted Odds Ratio [AOR] = 2.60; 95% confidence interval [CI]: (1.08 - 6.27) and public injection (AOR = 2.20; 95% CI: 1.09 - 4.43) were positively associated with recent non-fatal overdose.

Conclusions: Fentanyl injection and public injection were associated with an increased likelihood of non-fatal overdose. These findings underscore the need for drug checking, safer sources of opioids and safer injecting interventions as part of overdose prevention strategies.

Keywords: Fentanyl; illicit drugs; injection drug users; nonfatal overdose.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / poisoning*
  • British Columbia
  • Cross-Sectional Studies
  • Drug Overdose / etiology*
  • Drug Overdose / prevention & control*
  • Female
  • Fentanyl / administration & dosage
  • Fentanyl / poisoning*
  • Humans
  • Male
  • Middle Aged
  • Public Health*
  • Risk Factors

Substances

  • Analgesics, Opioid
  • Fentanyl

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