Piglet hypoxia during farrowing is common and can lead to increased stillbirth rates, reduced piglet vitality, and an increased risk of preweaning mortality. Magnesium sulfate (MgSO₄) has successfully been used as a neuroprotectant and readily crosses the placenta in humans. Based on this human data, the aim of this study was to determine if maternal dietary supplementation with MgSO₄ prior to farrowing would reduce the impact of piglet hypoxia during the peri-natal period. Five days prior to farrowing, Large White × Landrace sows were fed either standard lactation sow diet (Cont; n = 30) or lactation diet supplemented to deliver 21 g/day MgSO₄ (Mg; n = 31). There was no effect of treatment on the percentage of stillborn piglets (p > 0.05). However, Mg piglets tended to have higher vitality scores immediately after birth (p < 0.10), were quicker to suck, and had higher day one blood glucose concentrations when compared with Cont piglets (p < 0.05). Furthermore, hypoxic piglets born to Cont sows did not gain weight from birth to 24 h, but Mg piglets did (p < 0.05), suggesting improved colostrum ingestion. In conclusion, MgSO₄ may reduce the negative impacts of birth hypoxia, improving piglet vitality, and colostrum intake during the peri-natal period.
Keywords: colostrum; hypoxia; magnesium; piglet survival; thermoregulation; vitality.