Elevated IgE M1 prime transcripts in nasal tissues in patients with nasal polyps and asthma

J Allergy Clin Immunol. 2019 Feb;143(2):805-807. doi: 10.1016/j.jaci.2018.10.011. Epub 2018 Oct 22.

Authors

Heleen Scheerens¹, Ashley Smith², Olga Li², Lee Honigberg², Jeffrey M Harris², Gabriele Holtappels³, Claus Bachert⁴

Affiliations

¹ Genentech, Inc, South San Francisco, Calif. Electronic address: scheerens.heleen@gene.com.
² Genentech, Inc, South San Francisco, Calif.
³ Upper Airways Research Laboratory, ENT Department, Ghent University Hospital, Ghent, Belgium.
⁴ Upper Airways Research Laboratory, ENT Department, Ghent University Hospital, Ghent, Belgium; Division of ENT Diseases, CLINTEC, Karolinska Institute, Stockholm, Sweden.

PMID: 30359682
DOI: 10.1016/j.jaci.2018.10.011

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Asthma / immunology*
B-Lymphocytes / metabolism*
Chronic Disease
Disease Progression
Humans
Immunoglobulin Class Switching
Immunoglobulin E / genetics
Immunoglobulin E / metabolism*
Membrane Proteins / genetics
Membrane Proteins / metabolism*
Nasal Polyps / immunology*
Paranasal Sinuses / metabolism*
Polymerase Chain Reaction
Protein Domains / genetics
Protein Domains / immunology
Receptors, Antigen, B-Cell / genetics
Receptors, Antigen, B-Cell / metabolism*
Rhinitis / immunology*
Sinusitis / immunology*

Substances

Membrane Proteins
Receptors, Antigen, B-Cell
Immunoglobulin E