Extracorporeal Barbotage Detoxification of the Blood Plasma

Bull Exp Biol Med. 2018 Oct;165(6):820-822. doi: 10.1007/s10517-018-4273-9. Epub 2018 Oct 23.

Abstract

We studied the efficiency of bubbling air as a method of detoxification of the blood plasma and its mixtures with plasma substitutes from CCl4. The efficiency of detoxification depended on the characteristics of the obtained foams: foam forming ability, frequency rate, dispersion, stability of a foam skeleton, syneresis, etc. A hardware-software complex for extracorporeal blood plasma detoxification was developed and the programs for the control and regulation of this process were tested. Physical and mathematical models of toxicant excretion from the body during extracorporal blood detoxification were proposed. Verification of the mathematical model demonstrates high correspondence between the theoretical and experimental data.

Keywords: blood plasma; extracorporeal detoxification; foaming; foamy air barbotage; toxicant.

MeSH terms

  • Carbon Tetrachloride / chemistry*
  • Computers
  • Diffusion
  • Gases
  • Humans
  • Inactivation, Metabolic*
  • Kidneys, Artificial
  • Kinetics
  • Models, Theoretical
  • Plasma / chemistry*
  • Software
  • Tissue Engineering

Substances

  • Gases
  • Carbon Tetrachloride