[The role of molecular imaging (PET-CT) in the diagnostic and treatment pf prostate cancer]

Wien Med Wochenschr. 2019 Feb;169(1-2):12-14. doi: 10.1007/s10354-018-0668-5. Epub 2018 Oct 22.
[Article in German]

Abstract

Prostate cancer is the most frequent cancer type in men in industrialized countries. In case of biochemical recurrent disease of prostate cancer is molecular imaging with PET-CT or PET-MRI a very promising modality for the detection of local recurrence, lymph node involvement or distant metastasis. Of the so far implemented radiopharmaceuticals the radioactive labeled PSMA ligands (i. e. Ga-68 PSMA) have prevailed. There are also in the meanwhile treatment approaches with PSMA ligands (i. e. Lu-177 PSMA) in case of metastatic disease.

Keywords: PET; PSMA; Prostate cancer.

Publication types

  • Review

MeSH terms

  • Edetic Acid / analogs & derivatives
  • Gallium Radioisotopes
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Molecular Imaging*
  • Multimodal Imaging / methods
  • Neoplasm Recurrence, Local
  • Oligopeptides
  • Positron Emission Tomography Computed Tomography / methods*
  • Prostatic Neoplasms* / diagnostic imaging
  • Prostatic Neoplasms* / metabolism
  • Radiopharmaceuticals

Substances

  • Gallium Radioisotopes
  • Oligopeptides
  • Radiopharmaceuticals
  • Gallium-68
  • Edetic Acid