The Tectorial Membrane: Mechanical Properties and Functions

Cold Spring Harb Perspect Med. 2019 Oct 1;9(10):a033514. doi: 10.1101/cshperspect.a033514.

Abstract

The tectorial membrane (TM) is widely believed to play a critical role in determining the remarkable sensitivity and frequency selectivity that are hallmarks of mammalian hearing. Recently developed mouse models of human hearing disorders have provided new insights into the molecular, nanomechanical mechanisms that underlie resonance and traveling wave properties of the TM. Herein we review recent experimental and theoretical results detailing TM morphology, local poroelastic and electromechanical interactions, and global spread of excitation via TM traveling waves, with direct implications for cochlear mechanisms.

Publication types

  • Review

MeSH terms

  • Animals
  • Auditory Pathways / physiology
  • Biomechanical Phenomena
  • Cochlea / physiology*
  • Cochlea / ultrastructure
  • Cochlear Microphonic Potentials
  • Hair Cells, Auditory / physiology
  • Hearing / physiology*
  • Humans
  • Mice
  • Tectorial Membrane / physiology*
  • Tectorial Membrane / ultrastructure