Microfluidics-Based Biomaterials and Biodevices

Adv Mater. 2019 Nov;31(45):e1805033. doi: 10.1002/adma.201805033. Epub 2018 Oct 21.

Abstract

The rapid development of microfluidics technology has promoted new innovations in materials science, particularly by interacting with biological systems, based on precise manipulation of fluids and cells within microscale confinements. This article reviews the latest advances in microfluidics-based biomaterials and biodevices, highlighting some burgeoning areas such as functional biomaterials, cell manipulations, and flexible biodevices. These areas are interconnected not only in their basic principles, in that they all employ microfluidics to control the makeup and morphology of materials, but also unify at the ultimate goals in human healthcare. The challenges and future development trends in biological application are also presented.

Keywords: biomaterials; cell manipulations; flexible biodevices; human healthcare; microfluidics.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials*
  • Drug Delivery Systems / instrumentation
  • Humans
  • Lab-On-A-Chip Devices*
  • Mechanical Phenomena
  • Tissue Array Analysis / instrumentation

Substances

  • Biocompatible Materials