Relations between the blood lead level and metabolic syndrome risk factors

Public Health Nurs. 2019 Mar;36(2):118-125. doi: 10.1111/phn.12548. Epub 2018 Oct 21.

Abstract

Objective: This study is to examine the relations between the blood lead level, which has an effect on lipid metabolism in the body, and metabolic syndrome to establish a basic reference for the development of a local community health management program.

Design and sample: This study is a descriptive correlational study about verifying the relation between the blood lead level and metabolic syndrome risk factors. A total of 2,833 respondents' data were sampled on the 1st year (2016) data of the 7th Korea National Health and Nutrition Examination Survey conducted by the Korean Centers for Disease Control and Prevention (CDC).

Measures: The data were analyzed to explore blood lead level differences by demographic characteristics, correlations between the blood lead level and metabolic syndrome risk factors using chi-square test, Mann-Whitney U-test, Pearson correlation coefficient, and binary logistic regression.

Results: Systolic and diastolic blood pressure, triglycerides (TG), and FBS demonstrated a significant difference by blood lead level (p < 0.001). Systolic and diastolic blood pressure, waist circumference, and FBS and TG levels were positively correlated with blood lead level (p < 0.005), whereas high-density lipoprotein cholesterol was negatively correlated (r = -0.038, p < 0.005).

Conclusion: This study confirmed that the blood lead level was significantly correlated with all metabolic syndrome variables.

Keywords: health promotion; lead; metabolic syndrome; public health.

MeSH terms

  • Adult
  • Blood Pressure
  • Female
  • Humans
  • Lead / blood*
  • Lead Poisoning / blood
  • Logistic Models
  • Male
  • Mass Screening / statistics & numerical data*
  • Metabolic Syndrome / blood*
  • Metabolic Syndrome / diagnosis*
  • Middle Aged
  • Nutrition Surveys
  • Republic of Korea
  • Risk Factors
  • Socioeconomic Factors
  • Triglycerides / blood
  • Waist Circumference

Substances

  • Triglycerides
  • Lead