Gastrointestinal Disorders in Peritoneal Dialysis Patients

Am J Nephrol. 2018;48(5):319-325. doi: 10.1159/000494145. Epub 2018 Oct 19.

Abstract

Background: Gastrointestinal (GI) disorders in peritoneal dialysis (PD) patients are relatively understudied in the literature, even though they have a serious impact in the morbidity parameters and the quality of life for this group of patients. Various diagnostic tools have been used, including instrumental methods and questionnaires, invariably validated in comparative studies.

Summary: The prevalence of GI disorders is very high in PD patients. Compared to the haemodialysis patients they present a higher prevalence of reflux, eating dysfunction, gastroesophageal reflux, intestinal obstruction or adhesions and abdominal hernia. They may be divided into Gastric disorders (Gastroesophageal reflux disease, pathological Gastric emptying, Dyspepsia, Helicobacter pylori infection, peptic ulcers) and Intestinal disorders (Peritonitis, Diverticulosis, Constipation). Key Messages: The current paper is a review of the literature involving GI disorders in PD patients. This special group of patients with a special role of the peritoneal cavity and the GI motility in the physiology of their dialysis merit a larger number of studies dealing with the interrelation of the GI tract and the PD physiological, functional and pathophysiological parameters.

Keywords: CAPD; Gastrointestinal disorders; Peritoneal dialysis.

Publication types

  • Review

MeSH terms

  • Gastrointestinal Diseases / complications
  • Gastrointestinal Diseases / epidemiology*
  • Gastrointestinal Diseases / etiology
  • Humans
  • Kidney Failure, Chronic / complications
  • Kidney Failure, Chronic / therapy*
  • Peritoneal Dialysis / adverse effects*
  • Prevalence
  • Quality of Life*
  • Risk Factors