Wearable biofuel cells based on the classification of enzyme for high power outputs and lifetimes

Abstract

Wearable enzymatic biofuel cells would be the most prospective fuel cells for wearable devices because of their low cost, compactness and flexibility. As the high specificity and catalytic properties of enzymes, enzymatic biofuel cells (EBFCs) catalyze the fuel associated with the redox reaction and get electrical energy. Available biofuels such as glucose, lactate and pyruvate can be harvested from biofluids of sweat, tears and blood, which afford cells a favorable use in implantable and wearable devices. However, the development of wearable enzymatic biofuel cells requires significant improvements on the power density and enzymes lifetime. In this paper, some new advances in improving the performance of wearable enzymatic biofuel cells are reviewed based on the bioanode and biocathode by classifying single-enzyme and multi-enzyme catalysis system. Thereinto, the bioanode usually contains oxidases and dehydrogenases as catalyst, and the biocathode utilizes the catalysis of multi-copper oxidases (MCOs) in the single system. For further enhancing the power density, efforts to develop multi-enzyme catalysis strategies are discussed in bioanode and biocathode respectively. Moreover, some potential technologies in recent years, such as carbon nanodots, CNT sponges and mixed operational/storage electrode are summarized owing to notable efficiency and the capability of enhancing electron transfer on the electrode. Finally, major challenges and future prospects are discussed for the high power output, stable and practical wearable enzymatic biofuel cells.

Keywords: Bioanode; Biocathode; Electrode modification; Enzyme catalysis system; Wearable biofuel cells.