Polysaccharides from Chinese herbal medicine for anti-diabetes recent advances

Int J Biol Macromol. 2019 Jan:121:1240-1253. doi: 10.1016/j.ijbiomac.2018.10.072. Epub 2018 Oct 19.

Abstract

Diabetes mellitus (DM) is a chronic disease occurring when the body no longer produces adequate insulin or when it cannot use the produced insulin effectively. In recent years, more and more studies have revealed that Chinese materia medica polysaccharides are the key bioactive components of Chinese herbal medicine and have significant anti-diabetic effects with almost no side effects. In this review, we summarize 10 kinds of polysaccharides from Chinese herbal medicine which have effective anti-diabetes activities and the mechanism since 2014 to now. And it is hoped that this will provide an enlightenment for our researchers to design, research and development of polysaccharides.

Keywords: Chinese herbal medicine; Diabetes mellitus; Mechanism; Polysaccharides.

Publication types

  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus / drug therapy*
  • Drugs, Chinese Herbal / chemistry*
  • Humans
  • Hypoglycemic Agents / pharmacology*
  • Hypoglycemic Agents / therapeutic use
  • Polysaccharides / pharmacology*
  • Polysaccharides / therapeutic use

Substances

  • Drugs, Chinese Herbal
  • Hypoglycemic Agents
  • Polysaccharides