A detailed guide to lipid therapy in intestinal failure

Semin Pediatr Surg. 2018 Aug;27(4):242-255. doi: 10.1053/j.sempedsurg.2018.07.003. Epub 2018 Jul 31.

Abstract

Intravenous lipid emulsions are an integral part of nutrition therapy in the intestinal failure patient. In addition to being a concentrated source of non-protein calories, they provide the essential fatty acids necessary for growth and development. Depending upon the oil source used in these products, complications such as intestinal failure associated liver disease (IFALD) can occur. This review will discuss the risks and benefits associated with these products, especially as they relate to the pediatric intestinal failure patient.

Keywords: Essential fatty acid deficiency; Intestinal failure; Intestinal failure associated liver disease; Intravenous lipid emulsion; Omega-3 fatty acids; Parenteral nutrition.

Publication types

  • Review

MeSH terms

  • Fat Emulsions, Intravenous / therapeutic use*
  • Humans
  • Intestinal Diseases / complications
  • Intestinal Diseases / therapy*
  • Liver Diseases / etiology
  • Liver Diseases / prevention & control
  • Treatment Outcome

Substances

  • Fat Emulsions, Intravenous