A Survey of Web-Based Chemogenomic Data Resources

Methods Mol Biol. 2018:1825:3-62. doi: 10.1007/978-1-4939-8639-2_1.

Abstract

Chemogenomics is a comparatively nascent branch dealing with the effects of drugs and chemicals on molecular level systems. With the emergence of this new epoch, the quantity of data sources is also unprecedentedly increasing. Despite having a plethora of a databases, the variation in bioactivity measurement as well as bias toward specific protein studies, varied computational procedures and redundant information make data mining tedious, especially for newcomers in the field. In this chapter, we give an overview of hands-on data collection and domains of applicability from some useful Web-based chemogenomic resources that are accessible with nothing more than a Web browser. This overview can help assist users in acquiring chemogenomic datasets for their project at hand.

Keywords: ChEBI; ChEMBL; ChemProt; ChemSpider; Chemogenomic resources; Ligand-target data; PharmGKB; PubChem; STITCH; World Wide Web.

MeSH terms

  • Databases, Chemical*
  • Databases, Genetic*
  • Genomics / methods*
  • Humans
  • Web Browser