STI with Mycoplasma genitalium-more common than Chlamydia trachomatis in patients attending youth clinics in Sweden

Eur J Clin Microbiol Infect Dis. 2019 Jan;38(1):81-86. doi: 10.1007/s10096-018-3395-3. Epub 2018 Oct 16.

Abstract

The prevalence of Chlamydia trachomatis in Sweden is well known, whereas the prevalence of Mycoplasma genitalium is less well documented. Youth clinics offer free contraception advice, sexually transmitted infection (STI) testing and/or contact tracing for the age group 15-25 years. The main objective of this study was to determine the prevalence of STIs, the presence of symptoms and the role of contact tracing. From July 2013 to March 2014, 1001 persons, 509 women and 492 men, were included in this study of six youth clinics in the Region of Västra Götaland. Symptoms were registered and whether the patient was tested because of contract tracing. Collection of urine samples, testing, treatment and disease registration were performed according to clinical routines. Urine samples were analysed for C. trachomatis/N. gonorrhoeae on the Cobas 4800 system (Roche). M. genitalium was analysed by lab-developed PCR. Genital infection was present in 16.8%. The prevalence of M. genitalium was higher than for C. trachomatis (9.6% and 7.1%). Men with symptoms have a significantly higher relative risk for infection with M. genitalium or C. trachomatis compared to asymptomatic men, while there is no increase for women. Contact tracing is important since positive outcome has a high relative risk for both infections. The prevalence of M. genitalium was higher than C. trachomatis in this study population. Initial testing for both C. trachomatis and M. genitalium should at least be considered for young men presenting with symptoms of genital infection. In finding positive cases, contact tracing is of great importance.

Keywords: Chlamydia trachomatis; Mycoplasma genitalium; Prevalence; STI; Youth clinic.

MeSH terms

  • Adolescent
  • Adult
  • Chlamydia Infections / epidemiology*
  • Chlamydia trachomatis
  • Contact Tracing
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Mycoplasma Infections / epidemiology*
  • Mycoplasma genitalium
  • Prevalence
  • Sexually Transmitted Diseases / epidemiology*
  • Sweden / epidemiology
  • Young Adult