Intraluminal EWSR1-CREB1 gene rearranged, low-grade myxoid sarcoma of the pulmonary artery resembling extraskeletal myxoid chondrosarcoma (EMC)

Histopathology. 2019 Feb;74(3):526-530. doi: 10.1111/his.13773. Epub 2018 Dec 5.

Authors

Isabelle Opitz¹, Olivia Lauk¹, Didier Schneiter¹, Silvia Ulrich², Francesco Maisano³, Walter Weder¹, Beata Bode-Lesniewska⁴

Affiliations

¹ Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
² Department of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
³ Department of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland.
⁴ Institute of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.

PMID: 30326150
DOI: 10.1111/his.13773

No abstract available

Keywords: FISH; NGS; EWSR1-CREB1 fusion; pulmonary artery; pulmonary endarterectomy; sarcoma.

Publication types

Case Reports
Letter

MeSH terms

Chondrosarcoma / genetics*
Chondrosarcoma / pathology
Female
Gene Rearrangement*
Humans
Neoplasms, Connective and Soft Tissue / genetics*
Neoplasms, Connective and Soft Tissue / pathology
Oncogene Proteins, Fusion / genetics*
Pulmonary Artery / pathology*
Sarcoma / genetics*
Sarcoma / pathology
Vascular Neoplasms / genetics*
Vascular Neoplasms / pathology
Young Adult

Substances

EWSR1-CREB1 fusion protein, human
Oncogene Proteins, Fusion

Supplementary concepts

Chondrosarcoma, Extraskeletal Myxoid